They find targets at most tables, especially Northern Paladin, Exorcist, and Eastern Paladin
To do this though, you need to find various ways to actually discard these menacing threats
If you have Commander decks in white that go heavy on populate or commanders that make tokens like Rhys the Redeemed or Marneus Calgar, be sure to include this card
These decks are focused on all-out attack, often losing some creatures to blocks with every swing, because almost any sweeper or late-game threat will outclass them very quickly
Louisoix's Sacrifice is a strong sideboard card though, so bear that in mind
Throne of the High City : Land that can be sacrificed to become the Monarch, which allows you to draw an additional card at your end step