Its the most efficient way to selfmill and the more cards we flip in early turns of the game, the bigger the chances for finding the duo of Narcomoeba + Prized Amalgam or Silversmote Ghoul + Creeping Chill are
Thats the case we have here
You can just do it at any time
The real question is, what will you proliferate with it
In the wake of Marvel Rivals incorporating Knull, the villain from Cates and Stegmans run on Venom, into the games lore, Magic: The Gathering has delivered something for us Cates-Stegman Venomites (I just came up with that term now) in the form of a card called Venom, King in Black
Invasion of Belenon D-Tier: Three mana is just way too much to make a 2/2 creature, and five damage to end up with a Glorious Anthem is too much to make flipping worth it for most aggro decks