Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE nhs - CAS Number: 2307477-23-0 Molecular

- CAS Number: 2307477-23-0 Molecular Formula: C18H22ClN3O5 Molecular Weight: 395

32 SMILES COCC(=O)N[C@@H](CC1=CC=C(C=C1)C1=CC(Cl)=CC(Cl)=C1)[C@H](O)[C@@H](O)C(C)=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

MaP555-Azide is a highly cell-permeable andis a fluorogenic probe

64 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

COA           MSDS

Mal-Acetyl-Beta-Ala-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE nhs - CAS Number: 2307477-23-0 MolecularSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers