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Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg The conventional maleimidocaproyl (MC) unit

SKU: 13426761480

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Description

The conventional maleimidocaproyl (MC) unit is replaced by Mal-Propionyl-PEG2 moiety to enhance aqueous solubility

821 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

SiR650 Acid CAS Number 1426090-03-0 Related CAS N/A Molecular Formula C27H28N2O4Si Molecular Weight 472

DMF Shipping Conditions Room Temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

BG-Ac is a SNAP-tag substrate used as a small-sized label for comparison with other SNAP-tag substrates

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg The conventional maleimidocaproyl (MC) unitSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The payload is Exatecan,

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