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Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg BI-3802 has antitumor activity

SKU: 27329489345

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Description

BI-3802 has antitumor activity

the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes

Binfunctional amine-carboxylic acid linker

and Orally Bioavailable Small-Molecule GSPT1/2 Degraders from a Focused Library of Cereblon Modulators

151 Purity (HPLC) >= 95% Solubility DMSO

Azide-Dap(m-PEG4)-Val-Ala-PAB(m-PEG8)-MMAE Size:1mg BI-3802 has antitumor activitySOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase

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