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Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-PNP snap the chloro atom in Biotin-PEG4-halo

SKU: 28596094833

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Description

the chloro atom in Biotin-PEG4-halo is replaced with a methyl group

151 Purity (HPLC) >= 95% Solubility DMSO

486 SMILES: NCCCCCNC(=O)C1=CC=C2C(=C1)C(=O)OC21C2=CC=C(O)C=C2OC2=C1C=CC(O)=C2 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name Thalidomide-C3-PEG1-OH Synonyms Thalidomide-4'-C3-PEG1-OH CAS Number 2416133-06-5 Related CAS Molecular Formula C18H20N2O6 Molecular Weight 360

Carmichael

Mal-Propionyl-PEG8-Val-Ala-PAB(m-PEG4)-PNP snap the chloro atom in Biotin-PEG4-haloSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating

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