Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-PNP Size:25mg Product Name Thalidomide-O-acetamido-C5-acid Synonyms Thalidomide-4'-O-acetamido-C5-acid

Product Name Thalidomide-O-acetamido-C5-acid Synonyms Thalidomide-4'-O-acetamido-C5-acid CAS Number 2354352-06-8 Related CAS Molecular Formula C21H23N3O8 Molecular Weight 445

which can be conjugated to target protein ligands through straightforward chemical reactions

587 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCN2C(=O)C=CC2=O)=[N+](C)C)=C1 Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

and Escherichia coli dihydrofolate reductase (eDHFR)

489 SMILES OCCNC(=O)CN1CCN(CC(O)=O)CCN(CC(O)=O)CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Mal-Propionyl-PEG4-Val-Ala-PAB(m-PEG4)-PNP Size:25mg Product Name Thalidomide-O-acetamido-C5-acid Synonyms Thalidomide-4'-O-acetamido-C5-acidSOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating