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Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-PNP m-peg8-pab Cell Reports 2021

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Description

Cell Reports 2021

Product Name DOTA-heptyne Synonyms CAS Number n/a Related CAS Molecular Formula C23H39N5O7 Molecular Weight 497

Product Name Phthalimidinoglutarimide-5'-C4-amine HCl Synonyms CAS Number n/a Related CAS Molecular Formula C17H22ClN3O3 Molecular Weight 351

Product Name Pomalidomide-CO-C5-azide Synonyms Pomalidomide-4'-CO-C5-azide CAS Number 2227423-33-6 Related CAS Molecular Formula C19H20N6O5 Molecular Weight 412

Product Name DOTA-tris(t-Bu)ester-C4-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C39H67N7O10 Molecular Weight 794

Mal-Propionyl-PEG2-Val-Ala-PAB(m-PEG8)-PNP m-peg8-pab Cell Reports 2021SOLU KNEX cleavable linker features a Val Ala dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG2 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating

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