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Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE cy3 Product Name Fmoc-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS

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Description

Product Name Fmoc-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C55H72N6O16 Molecular Weight 1073

Product Name Lenalidomide-CO-PEG3-Cl Synonyms Lenalidomide-4'-CO-PEG3-Cl CAS Number n/a Related CAS Molecular Formula C22H28ClN3O7 Molecular Weight 481

467 Purity (HPLC) >= 95% Solubility DMSO

which can be conjugated to target protein ligands through straightforward chemical reactions

852 Purity (HPLC) >= 95% Solubility DMSO

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-MMAE cy3 Product Name Fmoc-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly

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