![OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA Size:1mg Product Name 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethan-1-amine Synonyms 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethanamine](https://cdn.shopify.com/s/files/1/0282/8953/1990/files/T70006.gif?v=1782946905)
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Product Name 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethan-1-amine Synonyms 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethanamine CAS Number 135630-61-4 Related CAS Molecular Formula C12H27N5 Molecular Weight 241
Product Name DOTA-PEG4-C2-azide Synonyms CAS Number n/a Related CAS Molecular Formula C26H48N8O11 Molecular Weight 648
Product Name DBCO-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8) Synonyms CAS Number Related CAS Molecular Formula C72H99N9O22 Molecular Weight 1442
CP-CPY is a SNAP-tag substrate containg CPY dye
m-PEG8 is attached to the commonly used self-immolative para-aminobenzyl (PAB) moiety to further increase aqueous solubility
OSu-PEG4-VC-PAB-DMEA-Duocarmycin SA Size:1mg Product Name 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethan-1-amine Synonyms 2-{4-[2-(piperazin-1-yl)ethyl]piperazin-1-yl}ethanamineOSu PEG4 vc PAB DMEA Duocarmycin SA is a cleavable ADC druglinker conjugate that couples the potent antitumor antibiotic Duocarmycin SA to an OSu PEG4 vc PAB DMEA linker. The DNA? modifying agents such as duocarmycin are increasingly used in the development of antibody? drug conjugates (ADCs), where they serve as highly potent cytotoxic payloads. Designed for ADC research, this construct supports efficient antibody conjugation, PEG4? enhanced
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