DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP 5' 55 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCBr)C(C)(C)C)C=C1 Purity (HPLC)

55 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Cell Reports 2021

Product Name Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C64H87FN12O19 Molecular Weight 1347

089 Purity (HPLC) >= 95% Solubility DMSO

ciently excited by the 543 nm spectral line of the Ar - Kr mixed gas laser commonly used in many confocal laser-scanning microscopes

DBCO-Lys(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG4)-PNP 5' 55 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCBr)C(C)(C)C)C=C1 Purity (HPLC)SOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to