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Propargyl-Gly(m-PEG4)-Val-Ala-PAB azide-dap-m-PEG4 Chloroquinaxoline sulfonamide (CQS) promotes the

SKU: 64782680543

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Description

Chloroquinaxoline sulfonamide (CQS) promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase for degadation

Product Name Pomalidomide-PEG4-C2-azide Synonyms Pomalidomide-4'-PEG4-C2-azide CAS Number 2271036-47-4 Related CAS Molecular Formula C23H30N6O8 Molecular Weight 518

Product Name Pomalidomide-acetamido-O-PEG2-C2-Cl Synonyms Pomalidomide-4'-acetamido-O-PEG2-C2-Cl CAS Number n/a Related CAS Molecular Formula C21H24ClN3O8 Molecular Weight 481

89 SMILES ClCCOCCOCCOCC(=O)NC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

349 SMILES OC(=O)CCCCOC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Propargyl-Gly(m-PEG4)-Val-Ala-PAB azide-dap-m-PEG4 Chloroquinaxoline sulfonamide (CQS) promotes theSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or

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