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DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg Product Name 5-FAM PEG3 alkyne

SKU: 84836984913

4.6
USD445.00 USD490.00

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Description

Product Name 5-FAM PEG3 alkyne Synonyms CAS Number N/A Related CAS Molecular Formula C30H27NO9 Molecular Weight 545

613 Purity (HPLC) >= 95% Solubility DMSO

66 Purity (HPLC) >= 95% Physical Appearance Red Solid Optical Properties Abs/Em Maxima: 558/578 nm Solubility DMSO

ZXH-1-161 can be used for researching multiple myeloma

Product Name Thalidomide-O-acetamido-PEG6-OH Synonyms Thalidomide-4'-O-acetamido-PEG6-OH CAS Number n/a Related CAS Molecular Formula C25H33N3O11 Molecular Weight 551

DBCO-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan Size:1mg Product Name 5-FAM PEG3 alkyneSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC

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