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Product Name Thalidomide-5'-O-C1-acid Synonyms CAS Number 2467425-53-0 Related CAS Molecular Formula C15H12N2O7 Molecular Weight 332
Trametinib binds KRS-MEK and disrupts RAF-MEK
The sulfonate groups enhance its water solubility and reduce nonspecific hydrophobic interactions
Product Name Azide-Lys(m-PEG4)-Val-Ala-PAB(m-PEG4) Synonyms CAS Number Related CAS Molecular Formula C41H70N8O14 Molecular Weight 899
364 SMILES OC(=O)CCOCCNC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only
Mal-Propionyl-Beta-Ala-Val-Ala-PAB(m-PEG8)-Exatecan fret Product Name Thalidomide-5'-O-C1-acid Synonyms CASSOLU KNEX cleavable linker features a Val Ala dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures,
