Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg Development of PDE6D and CK1a

Development of PDE6D and CK1a Degraders through Chemical Derivatization of FPFT-2216

519 Purity (HPLC) >= 95% Solubility DMSO

296 Purity (HPLC) >= 95% Solubility DMSO

684 SMILES: CN(C)C1=CC=C2C(OC3=CC(C=CC3=C2C2=CC=C(C=C2C([O-])=O)C(=O)NCCOCCOCCOCC#C)=[N+](C)C)=C1

Product Name BG-Cy3 Synonyms SNAP-Cy3 CAS Number Related CAS Molecular Formula C43H49N8O2 Molecular Weight 709

Azide-Dap(m-PEG4)-Gly-Gly-Phe-Gly-PAB(m-PEG8)-MMAE Size:5mg Development of PDE6D and CK1aSOLU KNEX cleavable linker features a Gly Gly Phe Gly (GGFG) peptide. In this product, a Azide Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The azide functional group is widely utilized in bioconjugation via click chemistry to enable efficient and selective attachment of biomolecules. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further