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the labeling efficiency of tetramethylrhodamine maleimides and iodoacetamides is often lower compared to that of other tetramethylrhodamine labeling dyes
Product Name MC-Val-Cit-PAB(m-PEG4)-PNP Synonyms CAS Number Related CAS Molecular Formula C45H62N8O16 Molecular Weight 971
Nature Chem 5
Product Name Negative Control of Biotin-PEG4-CA Synonyms Biotin-PEG4-PEG2-Heptane CAS Number Related CAS Molecular Formula C32H60N4O9S Molecular Weight 676
Product Name Propargyl-Gly(m-PEG4)-Val-Ala-OH Synonyms CAS Number Related CAS Molecular Formula C23H39N3O9 Molecular Weight 501
Azide-Hexanoyl-Val-Ala-PAB(m-PEG8)-Exatecan deuterium-labeled-ketone the labeling efficiency of tetramethylrhodamineSOLU KNEX cleavable linker features a Val Ala dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC
