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The player defeats monsters, using Isaac's tears as projectiles, and collects items which modify his appearance, attributes, and abilities, potentially creating powerful combinations

Each packet contains 4 cards

The Binding of Isaac 2011 video games Cancelled Nintendo 3DS games Criticism of Christianity Cultural depictions of Abraham Cultural depictions of Isaac Dungeon crawler video games Fiction about abortion Fiction about child abuse Flash games Four Horsemen of the Apocalypse in video games Game jam video games Indie games Linux games MacOS games Roguelike video games Seven deadly sins in popular culture Shooter games Single-player video games Twin-stick shooters Video games about children Video games about religion Video games based on the Bible Video games designed by Edmund McMillen Video games developed in the United States Video games scored by Danny Baranowsky Video games using procedural generation Windows games

Altered / intentionally modified cards Card with drawings, customizations or modifications that change the appearence of the original card

Collectors hate backlogs, dealers hate backlogs

Tropes exclusive to the Four Souls card game spin-off: Artistic License Religion: One of the cards for Dogma, "'Christian Broadcasts'", sarcastically jokes that one of the better-known voicelines during its in-game fight is definitely a Bible quote