How to Beat Infect Infect's biggest weakness is that it's solely tied to creatures
While classic rattlesnake cards like Mother of Runes and Selfless Spirit can be a perfectly serviceable way to protect yourself from targeted removal and board wipes, these cards are typically cast at sorcery speed
It shouldn't always be that easy, though I honestly could have gone for the win a turn or two earlier if I had wanted to
Mega Gengar ex works well in a dark box style deck, especially paired with Mega Sharpedo ex who can be your big hitter while Mega Gengar ex reduces the amount of prizes your opponent will take, enabling a favorable prize trade
If the game goes long however, you have creatures like Reckless Fireweaver to whittle down life totals while making treasures, and Academy Manufactor to make clues for more card draw
Grixis is a color combo that usually ends up heavy in spells, so to see a creature combat focused Commander that isnt reliant on reanimator is a breath of fresh air