This means that, if you draw a decent hand, you can often deal a few decisive blows before your opponent has got their Mewtwo ex or Celebi ex online
The opponent chooses whether to exile cards from the top of their library until they exile a nonland card or to exile the top four cards of their library
Special Summon 1 monster with the same name from your hand or GY
When El Shaddoll Construct is successfully summoned, its effect can be activated to send 1 Shaddoll card to the graveyard
Megaton's Fate has some versatility, but its first mode is basically a Shatter at sorcery speed, and its second mode isn't necessarily going to sweep the board (and those four milled cards aren't doing much either)
The most common forms of interaction for blue decks are bounce effects that return permanents to their owns hands, and what I call transmutation effects that remove a permanent and replace it with something differentthink Pongify and Curse of the Swine