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Edvotek Activity Kit - Water Quality Testing III: Multiplex PCR Testing of Water Contaminants Art-Design/Paints-Accessories/Paint-Blocks gives you an incredible arsenalDrinking water is routinely tested for contamination. If a screening tests positive, more sophisticated tests are required. One such test uses PCR in multiplex format. In this experiment, students will test for the presence of three separate, classroom safe organisms in a water sample using a single PCR reaction.