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MG132 (MG-132) _ 52801ES INF [Accession | P32971]

SKU: 49380141567

4.6
USD45.00 USD71.00

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Description

[Accession | P32971]

ELISA Data: Immobilized Human PLAU

The kits include concentrated assay reagents

Published 2021 Mar 17

S291277(IF:3

MG132 (MG-132) _ 52801ES INF [Accession | P32971]MG132 is a potent, reversible, cell permeable proteasome inhibitor (IC50=100 nM), more than 1000 fold more potent than ZLLal in inhibiting the ZLLL MCA degradation activity of the 20S proteasome. MG132 also inhibits the cell cycle and calpain required for cyclin degradation (IC50=1. 2 M), and induces neurite outgrowth in PC12 cells. In addition, MG132 inhibited IB degradation, thereby inhibiting NF B pathway activation. MG132 induces apoptosis of MPM

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