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PZRA004 exhibits attenuated binding activities to Fcγ receptors
Taranin AV
The balance between the surface RANK-mediated osteoclastogenesis and the decoy OPG-mediated inhibition fine tunes the activity of osteoclasts that ultimately controls the bone remodeling
the α chain of FcγRII receptors contains the signalling motif of either ITAM (immunoreceptor tyrosine-based activation motif) or ITIM (immunoreceptor tyrosine-based inhibition motif)
The IgG1 isotype Z-MAB® was generated by joining the variable regions of PZMU001 to the constant regions of a mouse IgG1 antibody
Human TRAIL-R3 Mouse IgG2a Wildtype Fc His-FLAG-Myc PZRA004 exhibits attenuated binding activitiesRAIL R3, also known as DcR1, was identified from EST data by two groups through searching for homologs of the TNFR1 death domain or the DR4 cysteine rich domain (CRD). Interacting protein(s): TRAIL (P7008F) Related products: TNF Receptor Superfamily Read all details below including Quick Specs. ** Please note: For orders over 1 mg, please inquire here Quick Specs Species: Human Catalog No.: P7057F Synonym: CD263, TNFRSF10C, DCR1, LIT, MGC149501,
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