ACE-031 stress-axis modulation

stress-axis modulation

It functions by binding to HDM-2

The potential benefits of PNC-27 are outlined below

Stress Response and Anxiolytic Models: In rodent elevated plus-maze

repeated dosing elevated circulating IGF-1

ACE-031 stress-axis modulationOverview ACE 031, also known as ramatercept or ACVR2B Fc, is a recombinant fusion protein consisting of the extracellular domain of human activin receptor type IIB (ActRIIB) fused to the Fc portion of human IgG1. It functions as a soluble decoy receptor that binds myostatin (GDF 8) and other TGF superfamily ligands (activins, GDF 11), preventing their interaction with endogenous receptors. It is widely used in laboratory and preclinical research as a