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Nystatin Antifungal Ointment 100,000 USP (Rx) Banana Stem Powder Save your skin by orderingNystatin Antifungal Ointment is a topical cream or ointment used to treat fungal infections of the skin. Nystatin is a polyene antifungal agent that binds to sterols in the fungal cell membrane, disrupting the cell membrane and leading to cell death. Nystatin is effective against a wide range of fungi, including Candida albicans. Nystatin is available as a cream, ointment, or powder, and is most commonly used to treat yeast infections of the skin,